Moving to the ends of the bag, on one end you find a simple pocket that runs the height of the bag. You might use this to store the hardback book you intend to read during your flight. The other end has a padded compartment designed for an iPad. Unzip this compartment and you find two interior pockets. Closest to the inside of the bag is the iPad's pouch, which is nicely padded on each side and has a Velcro strap over the top that prevents the iPad from slipping out. On the inner surface of the pocket, across from your iPad, is a zippered, mesh pocket you could use for storing your iPad's charger and a couple of cables.
The Weekender includes a padded carrying handle as well as a detachable padded shoulder strap. On the outside of the laptop pocket is a trolley strap--a stitched flap you can use to secure the bag to a larger rolling suitcase's retractable handle. On each end are nylon handles you can use to lift the bag out of an overhead bin or from the trunk of a car.
The construction of the Laptop Weekender is solid. The zippers are robust, and the handles are large enough to easily grasp. The material is also rugged and Skooba didn't skimp on the hardware or stitching. On the other hand, though the company makes a biggish deal about its patented Superbungee shoulder strap, I didn't find it more or less comfortable than any other reasonably well-padded shoulder strap I've used.
To test the Weekender I took the bag on a couple of trips. The first, it served as a heavily loaded tech bag for a week away with the family. As it was a working vacation, I hauled along a couple of laptops (one went inside the main storage area and the other in the dedicated laptop compartment), an Apple TV, two iPads, a couple of iPods, my iPhone, a dozen DVDs, and enough cables to strap down a rambunctious horse. Overall I found it easy to find the stuff I wanted without a lot of digging through the compartments.
I also used the Weekender as my only bag on a four day car-camping trip. This trip was far less tech-centric, so the bag's compartments were filled with activity-appropriate items: muddy shoes, thick socks, matches, a flashlight, a lantern, a hatchet, a water bottle, a wool sweater, and s'mores fixings. The bag stood up to some fairly rough treatment and, again, I appreciated the ability to organize my stuff in the bag's many pockets.